Domain annotation and functional classification


ProfileView

Functional classification of protein families using multiple single-domain probabilistic models. « View details »

MyCLADE

An accurate multi-source domain annotation server. « View details »

MetaCLADE

A multi-source domain annotation pipeline for quantitative metagenomic and metatranscriptomic functional profiling. « View details »

CLADE

A domain identification program based on a multi-source strategy. « View details »

DAMA

A multi-objective approach that accurately resolves protein domain architectures. « View details »

Plasmobase

A database of protein domain architectures found in Plasmodium full genomes. « View details »


Protein residue co-evolution


BIS

Coevolution analysis of amino-acid fragments in proteins. « View details »

BIS2

A very fast implementation of BIS for small sets of conserved protein sequences. « View details »

BIS2 Analyzer

Online analysis of coevolving amino-acid pairs in protein sequences, and identification of residue networks. « View details »

BIS2TreeAnalyzer

Coevolution analysis of large sets of conserved protein sequences. « View details »

iBIS2Analyzer

Phylogeny-driven coevolution analysis of protein families. « View details »

COVTree

Coevolution in overlapping sequences by tree analysis. « View details »

HCV Env

BIS2 co-evolution analysis of HCV envelope glycoproteins. « View details »

MaxSubTree

A method to detect coevolved amino acid networks in families of variable divergence. « View details »


Protein interactions


LEVELNET

Convenient, fast, and accurate environment to study protein-protein interaction networks. « View details »

PPDBv2 C-CDD

A knowledge base of cross-docking simulations. « View details »

CCD2PI

C-CD Benchmarks and partners identification. « View details »

CIPS

Combined Interface Propensity for decoy Scoring. « View details »

DLA-Ranker

Evaluation of protein docking conformations with Deep Learning. « View details »

DLA-Mutation

Evaluation of binding affinity changes with Deep Learning. « View details »

LISA

Local Interaction Signal Analysis: a protein-protein binding affinity estimation software. « View details »

INT(erface)Builder

A tool to screen millions of docking conformations and detect interfaces. « View details »


Protein interfaces


Soft Disorder

Soft disorder and interfaces at the scale of the PDB. « View details »

Protein assembly

Soft disorder to modulate the assembly path of protein complexes. « View details »

JET

A large-scale method to predict protein interfaces based on sequence sampling. « View details »

JET2

A sequence and structure-based method to predict protein-protein interfaces. « View details »

dynJET2

dynJET2 decrypts protein surfaces by combining evolution, geometry and molecular docking. « View details »

JET2DNA

JET2DNA predicts protein binding sites with DNA and RNA. « View details »

JET2 Viewer

JET2 predictions for more than 40 000 chains, occurring in Protein Data Bank (PDB) structures. « View details »


Phenotypes and genetic mutations


GEMME

An original and fast method that predicts mutational outcomes. « View details »

COMMA2

A method to identify highly sensitive residues and predict deleterious mutations. « View details »

COMMA

A method to dissect proteins dynamical architectures from conformational ensembles. « View details »


Genome organisation


PhyChro

To reconstruct phylogenies based on rearrangements. « View details »

CHROnicle

A package to reconstruct the history of genome rearrangements. « View details »

SPoRE

A mathematical model to predict double strand breaks and axis protein sites in meiosis. « View details »


Transcriptome analysis


MIReNA

A tool to find microRNAs with high accuracy and no learning at genome scale and from deep sequencing data. « View details »

MIReStruC

A tool to find microRNA structural clusters at genome scale and from deep sequencing data. « View details »

Parseq

Inferring transcription level from RNA-Seq read counts. « View details »

PureCLIP

Capturing protein-RNA interaction footprints from single-nucleotide CLIP-seq data. « View details »


NGS data analysis


S3A

A targeted domain assembler for fast functional profiling of metagenomic datasets. « View details »

Fiona

A parallel and automatic strategy for read error correction. « View details »

JRA

A split-alignment tool to infer structural variants from large short-read datasets. « View details »


Clustering for biological data


CLAG

Unsupervised non hierarchical clustering algorithm developed as an R package. « View details »

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