The availability of genomic data coming from sequencing and other high-throughput technologies radically changed the nature of biological investigations. Today, an organism and its changing environment can be considered together and in concert with a multitude of other organisms. The research topics of the unit concern all aspects of genomics in both prokaryotic and unicellular eukaryotic microorganisms, and possibly multicellular organisms.

In our laboratory experimentalists interact with computer scientists, mathematicians and physicists for defining new experimental questions, analyse large amount of data, model phenomena that characterize the new dimension within which biology lives today. Theoreticians generate new biological data that remain inaccessible to experiments today.

We are concerned with questions that are at the heart of biology:

• - genome architecture and evolution
• - genetic network architectures, their evolution across species, ecological relevance and environmental adaptation
• - modelling of complex biological systems
• - protein evolution in sequences and structures

GROUPS

• Analytical Genomics - Group Leader: Alessandra Carbone
• Biology of Genomes - Group Leader: Gilles Fischer
• Genetic Networks - Group Leader: Frederic Devaux
• Imaging of Nuclear Organization and DNA repair - Group Leader: Judith Mine-Hattab
• Machine Learning in Biology - Group Leader: Nataliya Sokolovska
• Mathematical Modeling in Biology - Group Leader: Delphine Salort
• Statistical Genomics and Biological Physics - Group Leader: Martin Weigt
• Synthetic and Systems Biology of Microalgae - Group Leader: Stéphane Lemaire
• Telomere & Genome Stability - Group Leader: Zhou Xu