Laboratory of Computational and Quantitative Biology (LCQB)
UMR 7238 CNRS - Sorbonne Université
You are here
Genomic evolution during a long-term experiment with Escherichia coli
Date:
Friday, April 10, 2015 - 11:00
Speaker:
Dominique Schneider
Address:
Campus des Cordeliers
Salle Déjérine (Esc B 2ème Etage),
15, rue de l'école de médecine 75006 Paris
Affiliation:
Laboratoire Adaptation et Pathogénie des Microorganismes CNRS UMR5163, Université Joseph Fourier, Grenoble (France)
Abstract:
Combining genomic analyses with evolution experiments provides a dynamic view of virtually all cellular processes. Indeed, the full revivable fossil record produced in such experiments can be investigated for phenotypic, genomic and global expression changes. During the longest-running evolution experiment with Escherichia coli, adaptive changes have been shown to strongly affect the sequence, structure and expression of evolved genomes, with sometimes unexpected phenotypic outcomes.
Type:
Interdisciplinary Seminar
Export:
