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Variability in viral pathogenesis: modeling the dynamic of acute and persistent infections.

TitleVariability in viral pathogenesis: modeling the dynamic of acute and persistent infections.
Publication TypeJournal Article
Year of Publication2017
AuthorsLidsky, PV, Andino, R, IM Rouzine
JournalCurr Opin Virol
Volume23
Pagination120-124
Date Published2017 Apr
ISSN1879-6265
Abstract

Virus infection often results in diverse outcomes. This variability of virus pathogenesis is not well understood. Here we revise theoretical arguments to further our understanding of factors controlling infection and its severity. We propose that variability in these factors results in different clinical outcomes, which ultimately ensure virus reproduction.

DOI10.1016/j.coviro.2017.05.001
Alternate JournalCurr Opin Virol
PubMed ID28551476