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Analytical Genomics

January 1, 2016

E.Laine and A.Carbone just published a new large-scale method to predict protein-protein interfaces based on sequence and structure information - Joint Evolutionary Trees 2 (JET2). It is the first time that a method highlights, with such a precision, information on distinguished binding sites, possibly overlapping each other.

To the Article and Software.

December 21, 2015

Interview of the German National Radio to A.Carbone, where she gives some highlights on protein-protein interactions.

July 12-16, 2015

The symposium The evolution of alternative splicing  is co-organized within the framework of the 2015 meeting of the Society for Molecular Biology and Evolution by E. Laine (LCQB), H. Richard (LCQB), and J. Roux (UNIL). The event will take place in Vienna, Austria.
Registration is now open.  Abstract submission for oral presentation closes on February 8th.

June 5, 2015

Kenneth Wolfe from University College Dublin ( ) will give a seminar on:
"Origin and evolution of a reversible DNA rearrangement mechanism: yeast mating-type switching”

October 8-10, 2014

The international meeting "Protein-Protein Interactions on the Genome Scale" is organized within the framework of the MAPPING project (Investissement d'Avenir en Bioinformatique) by A.Carbone.
The event will take place at UPMC, Jussieu Campus.
Registrations are open.

July 15-August 8, 2014

A.Carbone and E.Laine, from the Analytical Genomics Team, organize the ICS Summer School 2014 "Scientific Trends at the Interfaces - Bioinformatics and Scientific Visualization". Information on the school can be downloaded here.

February 8, 2014

A World Community Grid Lecture Series webcast describing the work done by the team and its collaborators on protein-protein interactions, within the framework of the "Help Cure Muscular Dystrophy" project can be found here.

January 23-24, 2014

Hugues Richard co-organizes the 10th edition of the workshop: Statistical Methods for (Post-) Genomics Data (SMPGD). 

The Laboratory Genomics of Microorganisms will hosts the meeting at the UPMC main campus, Paris, France.

October 28, 2013

The Analytical Genomics team releases the complete cross docking data of Mintseris Benchmark 2.0.

The analysis will are available in the article:

Anne Lopes,  Sophie Sacquin-Mora, Viktoriya Dimitrova, Elodie Laine, Yann Ponty, Alessandra Carbone. Protein-Protein Interactions in a Crowded Environment: An Analysis via Cross-Docking Simulations and Evolutionary Information. PLOS computational Biology (2013).

The dataset of protein-protein interactions was produced with over 7 months of computations on World Community Grid and with the help of thousands of internautes providing their computer time to dock about 300000 conformations per protein pair in the set of 28224 possible pairs in the Mintseris dataset.

July 1, 2013

Alessandra Carbone has been elected Senior Member at the Institut Universitaire de France.


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