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A tool to detect clusters of the coevolving positions in a multiple sequence alignment of highly conserved protein sequences

Coevolution in OVerlapped sequences by Tree analysis (COVTree) is a web server providing the online analysis of coevolving amino-acid pairs in overlapping genes, where residues might be located inside or outside the overlapping region.

Co-evolution analysis of the envelope glycoproteins E1 and E2 of the Hepatitis C Virus (HCV)

A method to identify highly sensitive residues and predicts deleterious mutations.

An empirical scoring function that estimates the binding affinity between two proteins, given the 3D structure of their complex.


Open Positions