The Laboratory of Computational and Quantitative Biology (LCQB), headed by A. Carbone, is an interdisciplinary laboratory working at the interface between biology and quantitative sciences. It is built to promote a balanced interaction of theoretical and experimental approaches in biology and to foster the definition of new experimental questions, data analysis and modeling of biological phenomena. Our projects address questions on biological structures and processes through the gathering of experimental measures, the in silico generation of new biological data that remain inaccessible to experiments today (modeling of biological systems), the development of statistical methods for data analysis, and the conception of original algorithms aimed to predictions. The lab is supported by the CNRS and Sorbonne Université.


June 16, 2022

The Laboratory of Computational and Quantitative Biology is searching for a new director who will take up his/her position on 01/01/2025. Please see the posting.

June 10, 2019

What can proteins tell us about how they interact and function together? At LCQB, we develop computational approaches to predict protein interactions, model protein social behaviour and infer the effect of mutations on protein interaction networks. We just posted this video explaining these ideas to the large public. 

Link to the french video

Link to the italian video

November 10, 2022

The LCQB is searching for an engineer (IR2 level). The position can be occupied immediately. Please see the posting.

November 10, 2022

New success for the iGEM team of Sorbonne Université: they received the Best Plant Synthetic Award! After one year of hard work in parallel of their classes and internships, our students (mostly from BMC and BIM master) received the Gold Medal for their project NAWI during the final conference (Grand Jamboree) held at the Paris Convention Center on October 26-28.


They were also nominated for Best Education and Best Presentation prizes out of 350 teams. Units implicated from IBPS: LCQB and LBD. Co-PIs: Frédérique Peronnet, Guillaume Garnier, Marco Da Costa, Pierre Crozet.

November 7, 2022

In parallel with her final year of PhD at the LCQB, Jeanne Le Peillet has just won two prizes for her business project Beink Dream: the regional Pépite IDF Prize and the National Pépite France Prize. While developing her project, she keeps on producting commissioned scientific illustrations for publications, conferences, patents and funding applications here.

Congratulations Jeanne!

November 7, 2022

Salomé Nashed, PhD student in the Genetic Networks team, has been

rewarded with the “prix Jeune Talent France L'Oréal-UNESCO pour les

Femmes et la Science”. Congratulations Salomé!

See article at SU here.

July 13, 2022

Edwin Rodriguez Horta, former PhD student in co-supervision between the University of Havana and the LCQB, receives a research price of the Academy of Sciences of Cuba for his thesis work.

July 12, 2022

Predicting species-specific mutation effects is a major challenge in genetics. Using diverged sequences, we learn protein sequence landscapes, which predict tolerated mutations in a species like E. coli and capture interactions between mutations.

See our article in Nature Communications.

June 8, 2022

Phylogeny matters in residue coevolution! try your favorite protein with iBIS2Analyzer. It works for conserved proteins like viral ones. See our last article in Nucleic Acids Research.
See also the press release by Sorbonne Université (in french).

May 10, 2022

This year, two of our alumni, Vittore Scolari and Riccardo Vicedomini have been recognized this year by the CNRS with two permanent researcher positions. Yasaman Karami was offered a permanent researcher position at INRIA, Beatriz Seoane a Chair of Junior Professor at the CNRS/U Paris-Saclay and Diego Zea, a Maitre de Conference position at U Paris-Saclay. Vittore was member of the Cosentino-Lagomarsino team, Riccardo, Yasaman, Beatriz and Diego of the Analytical Genomics team. In 2021, Edoardo Sarti, postdoc at LCQB in the Statistical Genomics and Biological Physics and in the Analytical Genomics teams, was offered a permanent researcher position at INRIA.


Congratulations to all!


Open Positions