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Telomere and Genome Stability

August 21, 2021

The analysis of the subtelomeres of a green alga, published in Nucleic Acids Research, is featured in this press release on the INSB website. The work, a collaboration between the LCQB ("Telomere and Genome Stability" and "Biology of Genomes" teams) and the IBPC, sheds light into the complexity and evolution of the subtelomeres, structures that are critical for genome integrity.

December 2, 2019

The "Emergence program" promoted by the "Ville de Paris" is awarded to projects encouraging the creation and the development of new research teams in the Paris region.
Zhou Xu received one of these recognitions for 2019.
 

December 6, 2018

The latest publication of the new LCQB team "Telomere and Genome Stability" (Héloïse Coutelier and Zhou Xu) makes the cover of the December issue of Genes & Development!    The article (Coutelier et al. 2018 Genes Dev.) shows that telomere-induced senescent cells can adapt to the DNA damage checkpoint safeguard mechanism to force cell division, leading to increased genome instability, with important ramifications for aging and cancer. The cover displays cells bearing a fluorescent reporter construct monitoring of the checkpoint status in single cells.

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