The Laboratory of Computational and Quantitative Biology (LCQB), headed by A. Carbone, is an interdisciplinary laboratory working at the interface between biology and quantitative sciences. It is built to promote a balanced interaction of theoretical and experimental approaches in biology and to foster the definition of new experimental questions, data analysis and modeling of biological phenomena. Our projects address questions on biological structures and processes through the gathering of experimental measures, the in silico generation of new biological data that remain inaccessible to experiments today (modeling of biological systems), the development of statistical methods for data analysis, and the conception of original algorithms aimed to predictions. The lab is supported by the CNRS and the University "Sorbonne Université".


March 1, 2016

A.E. Fortunato, M. Jaubert, J.P. Bouly, M. Thaler and A. Falciatore from the Diatom Functional Genomics team in collaboration with J.S. Bernardes (Statistical Genomics and Biological Physics), A. Carbone (Analytical Genomics) and other international collaborators published on The Plant Cell the paperDiatom Phytochromes Reveal the Existence of Far-Red-Light-Based Sensing in the Ocean.”  Full text paper.

Plant Cell Editor’s comment on this work.

January 1, 2016

E.Laine and A.Carbone just published a new large-scale method to predict protein-protein interfaces based on sequence and structure information - Joint Evolutionary Trees 2 (JET2). It is the first time that a method highlights, with such a precision, information on distinguished binding sites, possibly overlapping each other.

To the Article and Software.

December 21, 2015

Interview of the German National Radio to A.Carbone, where she gives some highlights on protein-protein interactions.

December 7-8, 2015

Marco Cosentino Lagomarsino co-organizes the 3rd edition of Quantitative Methods in Gene Regulation,
Corpus Christi College, Cambridge, UK. 

November 5-6, 2015

The 5th Cross Disciplinary Genomics meeting "Genomics of Microbial Communities" will be held at UPMC.
There is no participation fee but registration is required.

October 26, 2015

M.Punta, S.Longhi (University of Marseille) and A.Carbone organise the workshop "A DAY IN THE LIFE OF INTRINSICALLY DISORDERED PROTEINS: FROM COMPUTATION TO EXPERIMENTS" at the Ecole Nationale Supérieure de Chimie de Paris, Amphithéâtre Moissan.

No fee is required but registration is mandatory.

July 12-16, 2015

The symposium The evolution of alternative splicing  is co-organized within the framework of the 2015 meeting of the Society for Molecular Biology and Evolution by E. Laine (LCQB), H. Richard (LCQB), and J. Roux (UNIL). The event will take place in Vienna, Austria.
Registration is now open.  Abstract submission for oral presentation closes on February 8th.

July 7-10, 2015

Angela Falciatore co-organizes the International Conference "The molecular life of Diatoms 2015", 7-10 July 2015, Seattle, USA.

Registration is now open

June 5, 2015

Kenneth Wolfe from University College Dublin ( ) will give a seminar on:
"Origin and evolution of a reversible DNA rearrangement mechanism: yeast mating-type switching”

June 1, 2015

Ingrid Lafontaine (Biology of Genomes team) and Jean-Pierre Bouly (Diatom Genomics team), organize the symposium "Comunication between genomes"

Registration is now open


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