Shixin Ye-Lehmann

Zhao S, Shi J, Yu G, Li D, Wang M, Yuan C, Zhou H, Parizadeh A, Li Z, Guan M-X, Ye S. Photosensitive tyrosine analogues unravel site-dependent phosphorylation in TrkA initiated MAPK/ERK signaling. Communications Biology. 3(1), pp.706 (2020).

Zhang W, Hamouri F, Feng Z, Aujard I, Ducos B, Ye S, Weiss S, Volovitch M, Vriz S, Jullien L, Bensimon D. Control of Protein Activity and Gene Expression by Cyclofen-OH Uncaging. Chembiochem. 19(12), pp.1232-1238 (2018).

Tian M, Ye-Lehmann S Engineering light sensitive NMDARs. in Methods in Molecular Biology. Edited by: Szepetowski P. and Burnashev N. John Wiley & Sons, Inc. (2018)

Tian M, Ye S. Design of Light-Sensitive NMDARs by Genetically Encoded Photo-Cross-Linkers. Methods Mol Biol. 1677, pp.185-197 (2017).

Tian M, Wang Q, Ye-Lehmann S Elucidating GPCR structural function relationship through genetic code expansion. in Topics in Medicinal Chemistry. Edited by: Granier S. and Lebon G. 30, Springer. (2017)

Chen Y, Lu L, Ye S. Genetic Code Expansion and Optoproteomics. Yale J Biol Med. 90(4), pp.599-610 (2017).

Klippenstein V, Hoppmann C, Ye-Lehmann S, Wang L, Paoletti P. Optocontrol of glutamate receptor activity by single side-chain photoisomerization. Elife. 6, (2017).

Tian M, Wang Q, Yuan C, Ye S Structure and Function Studies of GPCRs by Site-Specific Incorporation of Unnatural Amino Aci. in Topics in Medicinal Chemistry. Springer. Berlin, Heidelberg. Springer,. (2017)

Tian M, Ye-Lehmann S. Allosteric regulation in NMDA receptors revealed by the genetically encoded photo-cross-linkers. Scientific Reports. 6, pp.34751 (2016).

Chen Y, Lu W, Gao N, Long Y, Shao Y, Liu M, Chen H, Ye S, Ma X, Liu M, Li D. Generation of obese rat model by transcription activator-like effector nucleases targeting the leptin receptor gene. Sci China Life Sci. (2016).

Chen Y, Ma J, Lu W, Tian M, Thauvin M, Yuan C, Volovitch M, Wang Q, Holst J, Liu M, Vriz S, Ye-Lehmann S, Wang L, Li D. Heritable expansion of the genetic code in mouse and zebrafish. Cell Res. (2016).

Simonson T, Ye-Lehmann S, Palmai Z, Amara N, Wydau-Dematteis S, Bigan E, Druart K, Moch C, Plateau P. Redesigning the stereospecificity of tyrosyl-tRNA synthetase. Proteins. 84(2), pp.240-53 (2016).

Wang J, Ye-Lehmann S, Gautheret D, Lehmann J. Development of a new method to identify aminoacylated RNA. BIO Web of Conferences. 2, pp.05003 (2014).

Zhu S, Riou M, C Yao A, Carvalho S, Rodriguez PC, Bensaude O, Paoletti P, Ye-Lehmann S. Genetically encoding a light switch in an ionotropic glutamate receptor reveals subunit-specific interfaces. Proc Natl Acad Sci U S A. 111(16), pp.6081-6 (2014).

Ye S, Riou M, Carvalho S, Paoletti P. Expanding the genetic code in Xenopus laevis oocytes. Chembiochem. 14(2), pp.230-5 (2013).

Naganathan S, Ye S, Sakmar TP, Huber T. Site-specific epitope tagging of G protein-coupled receptors by bioorthogonal modification of a genetically encoded unnatural amino acid. Biochemistry. 52(6), pp.1028-36 (2013).

Huber T, Naganathan S, Tian H, Ye S, Sakmar TP. Unnatural amino acid mutagenesis of GPCRs using amber codon suppression and bioorthogonal labeling. Methods Enzymol. 520, pp.281-305 (2013).

Ye S, Berger AAnn, Petzold D, Reimann O, Matt B, Koksch B. Chemical aminoacylation of tRNAs with fluorinated amino acids for in vitro protein mutagenesis. O’Hagan D (Eds.). Beilstein Journal of Organic Chemistry. 6, pp.40 (2010).

Ye S, Zaitseva E, Caltabiano G, Schertler GFX, Sakmar TP, Deupi X, Vogel R. Tracking G-protein-coupled receptor activation using genetically encoded infrared probes. Nature. 464(7293), pp.1386-9 (2010).

Ye S, Huber T, Vogel R, Sakmar TP. FTIR analysis of GPCR activation using azido probes. Nat Chem Biol. 5(6), pp.397 - 399 (2009).

Ye S, Köhrer C, Huber T, Kazmi M, Sachdev P, C Y Yan E, Bhagat A, RajBhandary UL, Sakmar TP. Site-specific incorporation of keto amino acids into functional G protein-coupled receptors using unnatural amino acid mutagenesis. J Biol Chem. 283(3), pp.1525-33 (2008).

Ye S, Discher BM, Strzalka J, Xu T, Wu SP, Noy D, Kuzmenko I, Gog T, Therien MJ, P Dutton L, J Blasie K. Amphiphilic four-helix bundle peptides designed for light-induced electron transfer across a soft interface. Nano Lett. 5(9), pp.1658-67 (2005).

Discher BM, Noy D, Strzalka J, Ye S, Moser CC, Lear JD, J Blasie K, P Dutton L. Design of amphiphilic protein maquettes: controlling assembly, membrane insertion, and cofactor interactions. Biochemistry. 44(37), pp.12329-43 (2005).

Ye S, Strzalka JW, Discher BM, Noy D, Zheng S, P Dutton L, J Blasie K. Amphiphilic 4-helix bundles designed for biomolecular materials applications. Langmuir. 20(14), pp.5897-904 (2004).

Ye S, Strzalka J, Churbanova IY, Zheng S, Johansson JS, J Blasie K. A model membrane protein for binding volatile anesthetics. Biophys J. 87(6), pp.4065-74 (2004).